ARNIs are a new drug combination of a neprilysin inhibitor and an ARB.
Commonly prescribed include:
What the Medication Does:
- Sacubitril/valsartan (Entresto)
Neprilysin is an enzyme that breaks down natural substances in the body that open narrowed arteries. By limiting the effect of neprilysin, it increases the effects of these substances and improves artery opening and blood flow, reduces sodium (salt) retention, and decreases strain on the heart.
Reason for Medication:
- For the treatment of heart failure